Before the 1840's, if someone needed an operation they needed to be held down by a group of strong men.
That all changed in 1847, when doctors discovered an anaesthetic that could render patients unconscious. It revolutionised surgery.
Professor Jamie Sleigh is from the Department of Anaesthesia of the Waikato Clinical School has been undertaking research into exactly how general anaesthetics affect the brain to cause unconsciousness, and says there is still a lot we don't know.